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::General Information
ID U0008
Creation Date 30 September 1997
Updating Date 30 September 1997
Standard Name Nanos translation control element (NANOS_TCE)
UTRSite Pattern
r1={au,ua,cg,gc,gu,ug}
p1=4...10 p2=6...9 cuggc r1~p2 0...3
p3=10...12 7...8 r1~p3[1,0,0] 0...2
r1~p1 p3:(p4=uauaua)
Random Expectation 4.0000000000 hits/kb
::Taxonomy
UTR Region 3'
Taxon Range Metazoa
::Description
Description The 3'UTR of drosophila nanos mRNA contains the essential signals for generating the nanos gradient emanating from the posterior pole of drosophila embryos. The polarized distribution of nanos is generated by the localization dependent translation of nanos mRNA in the pole plasm. The translation control element (TCE) consist of a 90-nt region located in the 3'UTR of nanos mRNA which is able to fold into a bipartite secondary structure that is recognized by Smaug repressor and at lea......
::Features
Feature Key NANOS_TCE
::Database Cross-references
Link
RFAM: RF00161
::Transcript(s) / Gene(s)
UTR(s)
Description Species Link Ref.
3' UTR in Drosophila melanogaster nanos (nos), mRNA. Drosophila melanogaster UTRef: 3DMER012985 [U1][U2]
Transcript(s)
Description Species Link Ref.
Drosophila melanogaster nanos (nos), mRNA. Drosophila melanogaster RefSeq: NM_057310 [T1][T2]
Gene(s)
Description Species Link Ref.
nanos (nos). Drosophila melanogaster EntrezGene: 42297 [G1][G2]
::Protein(s)
Binding Protein(s)
Description Species Link Ref.
Smaug isoform C in Drosophila melanogaster. Drosophila melanogaster RefSeq: NP_729442 [B1]
::References
ID [1]
Authors Crucs S.,Chatterjee S.,Gavis ER.
Title Overlapping but distinct RNA elements control repression and activation of nanos translation
Citation Mol Cell.5(3):457-67
Year 2000
ID [2]
Authors Gavis ER.,Lunsford L.,Bergsten SE.,and Lehmann R.
Title A conserved 90 nucleotide element mediates translational repression of nanos RNA
Citation Development 122(9):2791-800
Year 1996
ID [3]
Authors Dahanukar A & Wharton RP
Title The nanos gradient in drosophila embryos is generated by translational regulation
Citation Genes Dev. 10: 2610-2620
Year 1996
ID [U1]
Authors Gavis ER.,Lunsford L.,Bergsten SE.,and Lehmann R.
Title A conserved 90 nucleotide element mediates translational repression of nanos RNA
Citation Development 122(9):2791-800
Year 1996
ID [U2]
Authors Dahanukar A & Wharton RP
Title The nanos gradient in drosophila embryos is generated by translational regulation
Citation Genes Dev. 10: 2610-2620
Year 1996
ID [T1]
Authors Gavis ER.,Lunsford L.,Bergsten SE.,and Lehmann R.
Title A conserved 90 nucleotide element mediates translational repression of nanos RNA
Citation Development 122(9):2791-800
Year 1996
ID [T2]
Authors Dahanukar A & Wharton RP
Title The nanos gradient in drosophila embryos is generated by translational regulation
Citation Genes Dev. 10: 2610-2620
Year 1996
ID [G1]
Authors Gavis ER.,Lunsford L.,Bergsten SE.,and Lehmann R.
Title A conserved 90 nucleotide element mediates translational repression of nanos RNA
Citation Development 122(9):2791-800
Year 1996
ID [G2]
Authors Dahanukar A & Wharton RP
Title The nanos gradient in drosophila embryos is generated by translational regulation
Citation Genes Dev. 10: 2610-2620
Year 1996
ID [B1]
Authors Crucs S.,Chatterjee S.,Gavis ER.
Title Overlapping but distinct RNA elements control repression and activation of nanos translation
Citation Mol Cell.5(3):457-67
Year 2000