ID
U0008
Creation Date
30 September 1997
Updating Date
30 September 1997
Standard Name
Nanos translation control element (NANOS_TCE)
UTRSite Pattern
r1={au,ua,cg,gc,gu,ug}
p1=4...10 p2=6...9 cuggc r1~p2 0...3
p3=10...12 7...8 r1~p3[1,0,0] 0...2
r1~p1 p3:(p4=uauaua)
Random Expectation
4.0000000000 hits/kb
UTR Region
3'
Taxon Range
Metazoa
Description
The 3'UTR of drosophila nanos mRNA contains the
essential signals for generating the nanos gradient
emanating from the posterior pole of drosophila embryos.
The polarized distribution of nanos is generated by the
localization dependent translation of nanos mRNA in the
pole plasm. The translation control element (TCE) consist
of a 90-nt region located in the 3'UTR of nanos mRNA
which is able to fold into a bipartite secondary structure that is
recognized by Smaug repressor and at lea......
Feature Key
NANOS_TCE
Link
UTR(s)
Description
Species
Link
Ref.
3' UTR in Drosophila melanogaster nanos (nos), mRNA.
Drosophila melanogaster
UTRef: 3DMER012985
[U1] [U2]
Transcript(s)
Gene(s)
Binding Protein(s)
Description
Species
Link
Ref.
Smaug isoform C in Drosophila melanogaster.
Drosophila melanogaster
RefSeq: NP_729442
[B1]
ID
[1]
Authors
Crucs S.,Chatterjee S.,Gavis ER.
Title
Overlapping but distinct RNA elements control repression and activation of nanos translation
Citation
Mol Cell.5(3):457-67
Year
2000
ID
[2]
Authors
Gavis ER.,Lunsford L.,Bergsten SE.,and Lehmann R.
Title
A conserved 90 nucleotide element mediates translational repression of nanos RNA
Citation
Development 122(9):2791-800
Year
1996
ID
[3]
Authors
Dahanukar A & Wharton RP
Title
The nanos gradient in drosophila embryos is generated by translational regulation
Citation
Genes Dev. 10: 2610-2620
Year
1996
ID
[U1]
Authors
Gavis ER.,Lunsford L.,Bergsten SE.,and Lehmann R.
Title
A conserved 90 nucleotide element mediates translational repression of nanos RNA
Citation
Development 122(9):2791-800
Year
1996
ID
[U2]
Authors
Dahanukar A & Wharton RP
Title
The nanos gradient in drosophila embryos is generated by translational regulation
Citation
Genes Dev. 10: 2610-2620
Year
1996
ID
[T1]
Authors
Gavis ER.,Lunsford L.,Bergsten SE.,and Lehmann R.
Title
A conserved 90 nucleotide element mediates translational repression of nanos RNA
Citation
Development 122(9):2791-800
Year
1996
ID
[T2]
Authors
Dahanukar A & Wharton RP
Title
The nanos gradient in drosophila embryos is generated by translational regulation
Citation
Genes Dev. 10: 2610-2620
Year
1996
ID
[G1]
Authors
Gavis ER.,Lunsford L.,Bergsten SE.,and Lehmann R.
Title
A conserved 90 nucleotide element mediates translational repression of nanos RNA
Citation
Development 122(9):2791-800
Year
1996
ID
[G2]
Authors
Dahanukar A & Wharton RP
Title
The nanos gradient in drosophila embryos is generated by translational regulation
Citation
Genes Dev. 10: 2610-2620
Year
1996
ID
[B1]
Authors
Crucs S.,Chatterjee S.,Gavis ER.
Title
Overlapping but distinct RNA elements control repression and activation of nanos translation
Citation
Mol Cell.5(3):457-67
Year
2000