| ID |
U0008 |
|
| Creation Date |
30 September 1997 |
| Updating Date |
30 September 1997 |
|
| Standard Name |
Nanos translation control element (NANOS_TCE) |
| UTRSite Pattern |
r1={au,ua,cg,gc,gu,ug}
p1=4...10 p2=6...9 cuggc r1~p2 0...3
p3=10...12 7...8 r1~p3[1,0,0] 0...2
r1~p1 p3:(p4=uauaua)
|
| Random Expectation |
4.0000000000 hits/kb |
|
| UTR Region |
3' |
| Taxon Range |
Metazoa |
|
| Description |
The 3'UTR of drosophila nanos mRNA contains the
essential signals for generating the nanos gradient
emanating from the posterior pole of drosophila embryos.
The polarized distribution of nanos is generated by the
localization dependent translation of nanos mRNA in the
pole plasm. The translation control element (TCE) consist
of a 90-nt region located in the 3'UTR of nanos mRNA
which is able to fold into a bipartite secondary structure that is
recognized by Smaug repressor and at lea...... |
|
|
|
| Feature Key |
NANOS_TCE |
|
| Link |
|
|
| UTR(s) |
| Description |
Species |
Link |
Ref. |
| 3' UTR in Drosophila melanogaster nanos (nos), mRNA. |
Drosophila melanogaster |
UTRef: 3DMER012985 |
[U1][U2] |
|
| Transcript(s) |
|
| Gene(s) |
|
|
| Binding Protein(s) |
| Description |
Species |
Link |
Ref. |
| Smaug isoform C in Drosophila melanogaster. |
Drosophila melanogaster |
RefSeq: NP_729442 |
[B1] |
|
|
| ID |
[1] |
| Authors |
Crucs S.,Chatterjee S.,Gavis ER. |
| Title |
Overlapping but distinct RNA elements control repression and activation of nanos translation |
| Citation |
Mol Cell.5(3):457-67 |
| Year |
2000 |
| ID |
[2] |
| Authors |
Gavis ER.,Lunsford L.,Bergsten SE.,and Lehmann R. |
| Title |
A conserved 90 nucleotide element mediates translational repression of nanos RNA |
| Citation |
Development 122(9):2791-800 |
| Year |
1996 |
| ID |
[3] |
| Authors |
Dahanukar A & Wharton RP |
| Title |
The nanos gradient in drosophila embryos is generated by translational regulation |
| Citation |
Genes Dev. 10: 2610-2620 |
| Year |
1996 |
| ID |
[U1] |
| Authors |
Gavis ER.,Lunsford L.,Bergsten SE.,and Lehmann R. |
| Title |
A conserved 90 nucleotide element mediates translational repression of nanos RNA |
| Citation |
Development 122(9):2791-800 |
| Year |
1996 |
| ID |
[U2] |
| Authors |
Dahanukar A & Wharton RP |
| Title |
The nanos gradient in drosophila embryos is generated by translational regulation |
| Citation |
Genes Dev. 10: 2610-2620 |
| Year |
1996 |
| ID |
[T1] |
| Authors |
Gavis ER.,Lunsford L.,Bergsten SE.,and Lehmann R. |
| Title |
A conserved 90 nucleotide element mediates translational repression of nanos RNA |
| Citation |
Development 122(9):2791-800 |
| Year |
1996 |
| ID |
[T2] |
| Authors |
Dahanukar A & Wharton RP |
| Title |
The nanos gradient in drosophila embryos is generated by translational regulation |
| Citation |
Genes Dev. 10: 2610-2620 |
| Year |
1996 |
| ID |
[G1] |
| Authors |
Gavis ER.,Lunsford L.,Bergsten SE.,and Lehmann R. |
| Title |
A conserved 90 nucleotide element mediates translational repression of nanos RNA |
| Citation |
Development 122(9):2791-800 |
| Year |
1996 |
| ID |
[G2] |
| Authors |
Dahanukar A & Wharton RP |
| Title |
The nanos gradient in drosophila embryos is generated by translational regulation |
| Citation |
Genes Dev. 10: 2610-2620 |
| Year |
1996 |
| ID |
[B1] |
| Authors |
Crucs S.,Chatterjee S.,Gavis ER. |
| Title |
Overlapping but distinct RNA elements control repression and activation of nanos translation |
| Citation |
Mol Cell.5(3):457-67 |
| Year |
2000 |
