UTRSite Logo
user: guest

Signal Manager :: View

::General Information
ID U0013
Creation Date 03 March 1999
Updating Date 03 March 1999
Standard Name Tumor necrosis factor alpha 3'UTR cis-acting element (TNF)
UTRSite Pattern
uuauguuu 0...8 ar auauuuau surayynrru ugucw
Random Expectation 0.0 hits/kb
::Taxonomy
UTR Region 3'
Taxon Range Vertebrata
::Description
Description Tumor necrosis factor alpha (TNF-alpha) is a key cytokine regulator of the immune process and of the tissue homeostasis. The production of TNF-alpha is mainly controlled post-trascriptionally by cis-elements located in the 3'-UTR and which regulate mRNA stability and translation efficency. In addition to a class II AU-rich element (ARE2) previously found in the 3'-UTR of TNF-alpha mRNA, another RNA binding motif has been characterized about 150 nt downstream. This element contains ......
::Features
Feature Key TNF
::Transcript(s) / Gene(s)
UTR(s)
Description Species Link Ref.
3' UTR in Mus musculus tumor necrosis factor (Tnf), mRNA. Mus musculus UTRef: 3MMUR059721 [U1]
Transcript(s)
Description Species Link Ref.
Mus musculus tumor necrosis factor (Tnf), mRNA. Mus musculus RefSeq: NM_013693 [T1]
Gene(s)
Description Species Link Ref.
tumor necrosis factor (Tnf). Mus musculus EntrezGene: 21926 [G1]
::References
ID [1]
Authors Hel Z, Di Marco S and Radzioch D
Title Characterization of the RNA binding proteins forming complexes with a novel putative regulatory region in the 3'-UTR of TNF-alpha mRNA
Citation Nucleic Acids Res. 26: 2803-2812
Year 1998
ID [U1]
Authors Hel Z, Di Marco S and Radzioch D
Title Characterization of the RNA binding proteins forming complexes with a novel putative regulatory region in the 3'-UTR of TNF-alpha mRNA
Citation Nucleic Acids Res. 26: 2803-2812
Year 1998
ID [T1]
Authors Hel Z, Di Marco S and Radzioch D
Title Characterization of the RNA binding proteins forming complexes with a novel putative regulatory region in the 3'-UTR of TNF-alpha mRNA
Citation Nucleic Acids Res. 26: 2803-2812
Year 1998
ID [G1]
Authors Hel Z, Di Marco S and Radzioch D
Title Characterization of the RNA binding proteins forming complexes with a novel putative regulatory region in the 3'-UTR of TNF-alpha mRNA
Citation Nucleic Acids Res. 26: 2803-2812
Year 1998