| ID |
U0022 |
|
| Creation Date |
22 November 2002 |
| Updating Date |
22 November 2002 |
|
| Standard Name |
Proneural Box (PB) |
| UTRSite Pattern |
AAUGGAAGACAAU
|
| Random Expectation |
0.0000380273 hits/kb |
|
| UTR Region |
3' |
| Taxon Range |
Metazoa |
|
| Description |
The 3'UTR of three proneural genes (achaete, lethal of scute,
and atonal) encoding basic Helix-Loop-Helix (bHLH)
transcriptional activators that initiate neurogenesis in
Drosophila contain a conserved 13 nt long element, AAUGGAAGACAAU,
denoted as the proneural box (PB). The central 7 nt of the PB are
exactly complementary to the GY-box (GYB) present in the 3'UTR of
many Notch pathway target genes in Drosophila.
The predicted duplex interaction, generally more extended than
the 7-m...... |
|
|
|
| Feature Key |
PRONEURAL-BOX |
|
| UTR(s) |
| Description |
Species |
Link |
Ref. |
| 3'UTR in Drosophila melanogaster achaete (ac), mRNA. |
Drosophila melanogaster |
UTRef: 3DMER001188 |
[U1] |
|
| Transcript(s) |
| Description |
Species |
Link |
Ref. |
| Drosophila melanogaster achaete (ac), mRNA. |
Drosophila melanogaster |
RefSeq: NM_057476 |
[T1] |
|
| Gene(s) |
|
|
| ID |
[1] |
| Authors |
Lai E.C. & Posakony J.W. |
| Title |
Regulation of Drosophila neurogenesis by RNA:RNA duplexes? |
| Citation |
Cell 93:1103-1104 |
| Year |
1998 |
| ID |
[2] |
| Authors |
Lai, E. C., R. Bodner, J. Kavaler, G. Freschi, and J. W. Posakony |
| Title |
Antagonism of Notch signaling activity by members of a novel protein family encoded by the Bearded and Enhancer of split gene complexes |
| Citation |
Development 127: 291-306 |
| Year |
2000 |
| ID |
[U1] |
| Authors |
Lai E.C. & Posakony J.W. |
| Title |
Regulation of Drosophila neurogenesis by RNA:RNA duplexes? |
| Citation |
Cell 93:1103-1104 |
| Year |
1998 |
| ID |
[T1] |
| Authors |
Lai E.C. & Posakony J.W. |
| Title |
Regulation of Drosophila neurogenesis by RNA:RNA duplexes? |
| Citation |
Cell 93:1103-1104 |
| Year |
1998 |
| ID |
[G1] |
| Authors |
Lai E.C. & Posakony J.W. |
| Title |
Regulation of Drosophila neurogenesis by RNA:RNA duplexes? |
| Citation |
Cell 93:1103-1104 |
| Year |
1998 |
