ID |
U0023 |
Creation Date |
22 November 2002 |
Updating Date |
22 November 2002 |
Standard Name |
K-Box (KB) |
UTRSite Pattern |
p1=cTGTGATa[1,0,0] p1:(p2=TGTGAT)
|
Random Expectation |
0.1234110000 hits/kb |
UTR Region |
3' |
Taxon Range |
Metazoa |
Description |
Many Notch pathway target genes in Drosophila, including most
members of the basic helix-loop-helix repressor family and the
Bearded family, contain a series of conserved sequence motifs in
their 3' UTRs, including the Brd box, the K box, and the GY box.
The K box (cTGTGATa) is present in one or more copies in many of
these 3'UTRs and mediates negative post-transcriptional regulation,
mainly effected by decreased transcript levels. Regulation by the
K box is spatially and temporall...... |
|
Feature Key |
K-BOX |
UTR(s) |
Description |
Species |
Link |
Ref. |
3' UTR in Drosophila melanogaster araucan (ara), mRNA. |
Drosophila melanogaster |
UTRef: 3DMER010234 |
[U1] |
|
Transcript(s) |
Description |
Species |
Link |
Ref. |
Drosophila melanogaster araucan (ara), mRNA. |
Drosophila melanogaster |
RefSeq: NM_079321 |
[T1] |
|
Gene(s) |
|
ID |
[1] |
Authors |
Lai et al. |
Title |
The K box, a conserved 3' UTR sequence motif, negatively regulates accumulation of enhancer of split complex transcripts |
Citation |
Development 125:4077-88 |
Year |
1998 |
ID |
[2] |
Authors |
Lai E.C. |
Title |
Micro RNAs are complementary to 3' UTR sequence motifs that mediate negative post-transcriptional regulation |
Citation |
Nature Genetics. 30:363-4 |
Year |
2002 |
ID |
[U1] |
Authors |
Lai et al. |
Title |
The K box, a conserved 3' UTR sequence motif, negatively regulates accumulation of enhancer of split complex transcripts |
Citation |
Development 125:4077-88 |
Year |
1998 |
ID |
[T1] |
Authors |
Lai et al. |
Title |
The K box, a conserved 3' UTR sequence motif, negatively regulates accumulation of enhancer of split complex transcripts |
Citation |
Development 125:4077-88 |
Year |
1998 |
ID |
[G1] |
Authors |
Lai et al. |
Title |
The K box, a conserved 3' UTR sequence motif, negatively regulates accumulation of enhancer of split complex transcripts |
Citation |
Development 125:4077-88 |
Year |
1998 |