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::General Information
ID U0036
Creation Date 27 July 2004
Updating Date 27 July 2004
Standard Name Drosophila hairy mRNA localization element (HLE)
UTRSite Pattern
r1={au,ua,gc,cg,gu,ug}
p1=cauuuc acnn p2=cauu 0...1 cg ccrggaunn cgcn r1~p2 uugnuu 0...2 r1~p1
::Taxonomy
UTR Region 3'
Taxon Range Insecta
::Description
Description In the early embryo of drosophila several transcripts localize exclusively apically of the peripheral nuclei. Apical transport of hairy pair-rule mRNA is mediated by a 121 nt element located in the 3' untranslated region. This element comprises two stem-loop structures in which double-stranded stems have been observed to be essential for localization. Base pair identities within the stem are not essential but contribute to the efficiency of localization thus suggesting that specificity is me......
::Features
Feature Key HLE
::Transcript(s) / Gene(s)
UTR(s)
Description Species Link Ref.
3' UTR in Drosophila melanogaster hairy (h), transcript variant B, mRNA. Drosophila melanogaster UTRef: 3DMER009739 [U1]
Transcript(s)
Description Species Link Ref.
Drosophila melanogaster hairy (h), transcript variant B, mRNA Drosophila melanogaster RefSeq: NM_001014577 [T1]
Gene(s)
Description Species Link Ref.
hairy (h). Drosophila melanogaster EntrezGene: 38995 [G1]
::References
ID [1]
Authors Bullock SL, Zicha D and Ish-Orowicz D
Title The Drosophila hairy RNA localization signal modulates the kinetics of cytoplasmic mRNA transport.
Citation EMBO J. 22: 2484-2494.
Year 2003
ID [U1]
Authors Bullock SL, Zicha D and Ish-Orowicz D
Title The Drosophila hairy RNA localization signal modulates the kinetics of cytoplasmic mRNA transport.
Citation EMBO J. 22: 2484-2494.
Year 2003
ID [T1]
Authors Bullock SL, Zicha D and Ish-Orowicz D
Title The Drosophila hairy RNA localization signal modulates the kinetics of cytoplasmic mRNA transport.
Citation EMBO J. 22: 2484-2494.
Year 2003
ID [G1]
Authors Bullock SL, Zicha D and Ish-Orowicz D
Title The Drosophila hairy RNA localization signal modulates the kinetics of cytoplasmic mRNA transport.
Citation EMBO J. 22: 2484-2494.
Year 2003