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::General Information
ID U0037
Creation Date 27 July 2004
Updating Date 27 July 2004
Standard Name Myelin Basic Protein Localization Element (MBP-A2RE11)
UTRSite Pattern
gswcacy GCCAwGGAGsC AsAsAGC
Random Expectation 0.0 hits/kb
::Taxonomy
UTR Region 3'
Taxon Range Vertebrata
::Description
Description Localization of myelin basic protein (MBP) mRNA to the myelin compartment in oligodendrocytes requires a short sequence element - whose core element is 11 nt long - located in the 3'UTR and interacting with heterogeneous nuclear protein A2 (hnRNP A2). Oligodendrocyte transport occurs via mRNA packaging into granules in the nucleus followed by export to cytoplasm and then microtubule- or microfilament-mediated transport to the final destination.
::Features
Feature Key MBP-A2RE11
::Transcript(s) / Gene(s)
UTR(s)
Description Species Link Ref.
3'UTR in Mus musculus myelin basic protein (Mbp), transcript variant 7,mRNA. Mus musculus UTRef: 3MMUR056217 [U1]
Transcript(s)
Description Species Link Ref.
Mus musculus myelin basic protein (Mbp), transcript variant 7,mRNA. Mus musculus RefSeq: NM_010777 [T1]
Gene(s)
Description Species Link Ref.
myelin basic protein (Mbp). Mus musculus EntrezGene: 17196 [G1]
::References
ID [1]
Authors Ainger K, Avossa D, Diana AS, Barry C, Barbarese E, Carson JH.
Title Transport and localization elements in myelin basic protein mRNA.
Citation J Cell Biol. 1997 138(5):1077-87.
Year 1997
ID [U1]
Authors Ainger K, Avossa D, Diana AS, Barry C, Barbarese E, Carson JH.
Title Transport and localization elements in myelin basic protein mRNA.
Citation J Cell Biol. 1997 138(5):1077-87.
Year 1997
ID [T1]
Authors Ainger K, Avossa D, Diana AS, Barry C, Barbarese E, Carson JH.
Title Transport and localization elements in myelin basic protein mRNA.
Citation J Cell Biol. 1997 138(5):1077-87.
Year 1997
ID [G1]
Authors Ainger K, Avossa D, Diana AS, Barry C, Barbarese E, Carson JH.
Title Transport and localization elements in myelin basic protein mRNA.
Citation J Cell Biol. 1997 138(5):1077-87.
Year 1997