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::General Information
ID U0038
Creation Date 27 July 2004
Updating Date 27 July 2004
Standard Name Protamine P1 3'UTR Y-Box recognition site (Protamine-YRS)
UTRSite Pattern 
ca 0...4 wccaycnna 0...1 ctcctgcntga
::Taxonomy
UTR Region 3'
Taxon Range Metazoa
::Description
Description Protamine (Prm) mRNAs are translationally repressed for several days during male germ cell differentiation. Translational delay of Prm-1 mRNA involves the binding of Y-Box proteins MSY2 and MSY4 to a conserved region in the 3' most nt of the 3'UTR. The consensus site, denoted Y-Box Recognition Site (YRS) has been defined by mutational analysis and tested by the yeast three-hybrid system.
::Features
Feature Key Protamine-YRS
::Transcript(s) / Gene(s)
UTR(s)
Description Species Link Ref.
3' UTR in Mus musculus protamine 1 (Prm1), mRNA. Mus musculus UTRef: 3MMUR034288 [U1]
Transcript(s)
Description Species Link Ref.
Mus musculus protamine 1 (Prm1), mRNA. Mus musculus RefSeq: NM_013637 [T1]
Gene(s)
Description Species Link Ref.
Prm1 protamine 1. Mus musculus EntrezGene: 19118 [G1]
::Protein(s)
Binding Protein(s)
Description Species Link Ref.
Mus musculus Y box protein 2 (Ybx2). Mus musculus RefSeq: NP_058571 [B1]
::References
ID [1]
Authors Giorgini F, Davies HG, Braun RE.
Title MSY2 and MSY4 bind a conserved sequence in the 3' untranslated region of protamine 1 mRNA in vitro and in vivo.
Citation Mol Cell Biol. 2001 Oct;21(20):7010-9.
Year 2001
ID [U1]
Authors Giorgini F, Davies HG, Braun RE.
Title MSY2 and MSY4 bind a conserved sequence in the 3' untranslated region of protamine 1 mRNA in vitro and in vivo.
Citation Mol Cell Biol. 2001 Oct;21(20):7010-9.
Year 2001
ID [T1]
Authors Giorgini F, Davies HG, Braun RE.
Title MSY2 and MSY4 bind a conserved sequence in the 3' untranslated region of protamine 1 mRNA in vitro and in vivo.
Citation Mol Cell Biol. 2001 Oct;21(20):7010-9.
Year 2001
ID [G1]
Authors Giorgini F, Davies HG, Braun RE.
Title MSY2 and MSY4 bind a conserved sequence in the 3' untranslated region of protamine 1 mRNA in vitro and in vivo.
Citation Mol Cell Biol. 2001 Oct;21(20):7010-9.
Year 2001
ID [B1]
Authors Giorgini F, Davies HG, Braun RE.
Title MSY2 and MSY4 bind a conserved sequence in the 3' untranslated region of protamine 1 mRNA in vitro and in vivo.
Citation Mol Cell Biol. 2001 Oct;21(20):7010-9.
Year 2001