| ID |
U0046 |
|
| Creation Date |
05 August 2008 |
| Updating Date |
05 August 2008 |
|
| Standard Name |
Thiamin pyrophosphate riboswitch (TPP_riboswitch) |
| UTRSite Pattern |
r1={au,ua,gc,cg,gu,ug}
p1=gg g p2=u p3=gyyug 5...50 r1~p3 ugagaa[1,0,0] r1~p2 gu r1~p1 cuuugaa[2,0,0] p4=ccu gan p5=cagg[1,0,0] ruaaur[2,0,0] r1~p5 cgn r1~p4 ga gugugc[1,0,0]
|
|
|
| UTR Region |
3' |
| Taxon Range |
Viridiplantae |
|
| Description |
The 3' region of the thiamine biosynthesis gene THIC contains a riboswitch aptamer (i.e. a RNA motif adopting alternate structures depending on the binding of a metabolite) sensing the thiamine pyrophosphate (TPP) concentration. In some plant species the TPP riboswitch has been also found in THI1, another gene of thiamin biosynthesis.The TPP riboswitch, whose structure has been confirmed by crystal structure resolution (Thore et al. 2006), consists of five helices, termed P1 to P5, and h...... |
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|
| Image |
 |
|
| Feature Key |
TPP_riboswitch |
|
| UTR(s) |
| Description |
Species |
Link |
Ref. |
| 3'UTR in Arabidopsis thaliana catalytic AT2G29630 transcript variant AT2G29630.2 mRNA |
Arabidopsis thaliana |
UTRef: CR353599 |
[U1] |
|
| Transcript(s) |
| Description |
Species |
Link |
Ref. |
| Arabidopsis thaliana thiamine biosynthesis family protein / thiC family protein (AT2G29630) mRNA, complete cds |
Arabidopsis thaliana |
RefSeq: NM_179804 |
|
|
| Gene(s) |
| Description |
Species |
Link |
Ref. |
| AT2G29630 thiamine biosynthesis family protein / thiC family protein |
Arabidopsis thaliana |
EntrezGene: AT2G29630 |
|
|
|
| ID |
[1] |
| Authors |
Bocobza S, Adato A, Mandel T, Shapira M, Nudler E, Aharoni A. |
| Title |
Riboswitch-dependent gene regulation and its evolution in the plant kingdom. |
| Citation |
Genes Dev. 2007 Nov 15; 21(22): 2874-9 |
| Year |
2007 |
| ID |
[2] |
| Authors |
Thore S, Leibundgut M, Ban N. |
| Title |
Structure of the eukaryotic thiamine pyrophosphate riboswitch with its regulatory ligand. |
| Citation |
Science 2006 May 26; 312(5777): 1208-11 |
| Year |
2006 |
| ID |
[3] |
| Authors |
Wachter A, Tunc-Ozdemir M, Grove BC, Green PJ, Shintani DK, Breaker RR. |
| Title |
Riboswitch control of gene expression in plants by splicing and alternative 3' end processing of mRNAs. |
| Citation |
Plant Cell 2007 Nov; 19(11): 3437-50 |
| Year |
2007 |
| ID |
[U1] |
| Authors |
Wachter A, Tunc-Ozdemir M, Grove BC, Green PJ, Shintani DK, Breaker RR. |
| Title |
Riboswitch control of gene expression in plants by splicing and alternative 3' end processing of mRNAs. |
| Citation |
Plant Cell 2007 Nov; 19(11): 3437-50 |
| Year |
2007 |
